Background Multiple COVID-19 vaccines appear to be safe and efficacious, but only high-income countries have the resources to procure sufficient vaccine doses for most of their eligible populations. The World Health Organization has published guidelines for vaccine prioritisation, but most vaccine impact projections have focused on high-income countries, and few incorporate economic considerations. To address this evidence gap, we projected the health and economic impact of different vaccination scenarios in Sindh province, Pakistan (population: 48 million).
Methods We fitted a compartmental transmission model to COVID-19 cases and deaths in Sindh from 30 April to 15 September 2020 using varying assumptions about the timing of the first case and the duration of infection-induced immunity. We then projected cases and deaths over 10 years under different vaccine scenarios. Finally, we...
Dear Editor,We have read with great interest, a recent article highlighting the impact of co-epidemics of COVID-19 and infectious diseases on Pakistan’s overwhelmed healthcare system.1 SARS-CoV-2 is causing mild illnesses to even severe pneumonia cases in patients having co-morbidities. According to the World Health Organization (WHO), by January 3, 2021, COVID-19 has been the cause of 79 million active cases and 1.7 million deaths worldwide. In Pakistan, conditions of COVID-19 are worryingly worsening; there was an alarming resurgence of more than 14 809 new cases recorded last week (67 new cases per 1 million), with a rise of about 45%. On January 4, 2021, about 0.46 million infected cases, and 9 thousand deaths were reported in Pakistan, as shown in Fig. 1
(a).2 Simultaneously, pneumonia, either caused by viruses or bacteria, is more prevalent in the winter and autumn season. The...
A pandemic coronavirus infectious disease-2019 (COVID-19) was first originated in December 2019 in Wuhan, China. The entire world was locked down along with China to prevent the local transmission and wide geographical spread . On the 30th of January, 2020, the World Health Organization (WHO) declared the COVID-19 as public health emergency due to the increasing number of cases around the world . The WHO data on 7 May 2020 showed more than 3588700 confirmed and 247500 death cases of COVID-19 around the world . Taking into account the transmission, morbidity, and mortality of COVID-19, it is observed that most of the developed countries having advanced healthcare systems along with using their innovative research have been failed to cope with COVID-19. On the other hand, developing countries with their struggling and compromised healthcare system are even failed to record the...
The COVID-19 pandemic has affected about 210 countries with more than 67 million confirmed cases and over 1.5 million deaths across the globe including Pakistan. Considering the population density, health care capacity, existing poverty and environmental factors with more than 420,000 infected people and about 8300 plus mortalities, community transmission of the coronavirus happened rapidly in Pakistan. This paper analyses the short- and long-term effects of COVID-19 peak on the socio-economic and environmental aspects of Pakistan. According to the estimates, an economic loss of about 10%, i.e. 1.1 trillion PKR, will be observed in the FY 2021. Certain pandemic impediment measures like lockdowns, social distancing and travel restrictions taken by the Government have been thoroughly analysed to determine how they impacted the livelihoods of nearly 7.15 million workers. Consequently, a...
Purpose: A novel coronavirus, SARS-CoV-2 was identified as the cause of COVID-19 eventually led to the declaration of Public health emergency of international concern and a pandemic by WHO due to its exponential global spread. Present study was conducted to investigate the impact of second wave of pandemic on mental wellbeing and social behaviors among university students of Pakistan during this crucial period of COVID-19 infection. Methods: A cross-sectional analytical study was designed to evaluate the psychosocial impact during the current COVID-19 outbreak among the students of The Islamia University of Bahawalpur, Pakistan. Snowball sampling or chain referral sampling procedure was adopted to recruit the participants in the study. Verbal informed consent was taken from all participants before recruitment in the study irrespective of their gender, age and socioeconomic status....
Covid-19 has adversely impacted the health care organizations by over burdening with Covid patients and suspending the elective surgeries and clinics. Hospitalization during pandemic may increase health cost of patients for elective and emergency procedure due to extra cost of covid testing and isolation. A single center retrospective study was conducted to quantify losses due to postponement of elective surgeries and extra cost for procurement of PPEs. The secondary objective was to see the effect of Covid -19 on the total costs of inpatient care during Covid era. We included all the patients admitted in orthopedic section for operative intervention of fractures and elective procedures from January 1, 2020 to May 31, 2020. We divided this period into two halves; the first half was from January first to March 15 named as PreCovid Era and second half was from March 16, to May 31,...
The disruptions caused by the COVID-19 pandemic have devastating impact over vaccination programs around the globe especially in underdeveloped countries. The delays in immunization campaigns could increase infectious diseases such as polio, measles, and human papillomavirus. The pandemic is overstretching the health-care sectors and countries with limited capacity to deal major outbreaks are at breaking point. In accordance with World Health Organization (WHO), more than 116 million infants were vaccinated in 2019, and still more than 13 million children miss vaccination around the world and that the number could have been increased due to COVID-19.1
During the ongoing COVID-19 pandemic, Pakistan has had to delay vaccination for another life-threatening contagion, poliovirus. Since April, around 40 million children missed the polio vaccination due to the cancellation of vaccination...
The COVID-19 pandemic has disrupted health and health systems worldwide, and most countries have still not recovered from the immediate effects of the increased mortality and morbidity due to severe acute respiratory syndrome coronavirus 2 infection.1 This, in addition to the devastating economic consequences of the prolonged lockdowns, will challenge both developed and developing countries irrespective of their health infrastructure for years to come. It is predicted that these adverse health consequences will disproportionately affect the most vulnerable members of society—our children.2 Although most children are going to recover uneventfully from the infection, the impact of the disruption on the usual care of children such as school, sports and health-related activities including routine immunisations and preventative care visits is predicted to have severe consequences for...
To the Editor,
A recent report reviewed the Poliomyelitis (polio) epidemiology in Pakistan.
Pakistan is currently showing a very high number of COVID‐19 cases.
The outbreak of COVID‐19 has been known to cause by SARS‐CoV‐2, a novel coronavirus that emerged by the end of December 2019. By 19th June 2020, COVID‐19 has claimed the lives of 450 686 people and has been reported to infect almost 8 385 440 people worldwide.
Pakistan has reported 4944 cases in a single day, taking the toll of total infected cases to 165 062, and 3229 people have lost the battle of life against COVID‐19
(Figure 1). Another health emergency; Polio is looming as the country is battling against the COVID‐19 pandemic. Poliomyelitis is an infectious disease caused by Poliovirus that is a serotype of the specie Enterovirus C belonging to the family Picornaviridae. Poliovirus is a...